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1

Lectin and alliinase are the predominant proteins in nectar from leek (Allium porrumL.) flowers

Willy J. Peumans, Koen Smeets, Karel Van Nerum, Fred Van Leuven, Els J. M. Van Damme

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 630 KB

english, 1997

2

Garlic (Allium sativum) chitinases: characterization and molecular cloning

Els J. M. Van Damme, Pieter Willems, Sophie Torrekens, Fred Van Leuven, Willy J. Peumans

Journal:

Physiologia Plantarum

Année:

1993

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1993

3

Secretases as targets for the treatment of Alzheimer's disease: the prospects

Ilse Dewachter, Fred Van Leuven

Journal:

The Lancet Neurology

Année:

2002

Langue:

english

Fichier:

PDF, 725 KB

english, 2002

4

Characterization and molecular cloning of mannose-binding lectins from the Orchidaceae species Listera ovata, Epipactis helleborine and Cymbidium hybrid

Els J. M. VAN DAMME, Koen SMEETS, Sophie TORREKENS, Fred VAN LEUVEN, Willy J. PEUMANS

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.27 MB

english, 1994

5

A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species

Franky R.G. Terras, Sophie Torrekens, Fred Van Leuven, Rupert W. Osborn, Jozef Vanderleyden, Bruno P.A. Cammue, Willem F. Broekaert

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 941 KB

english, 1993

6

Differential expression of brain proteins in glycogen synthase kinase-3 transgenic mice: A proteomics point of view

Kelly Tilleman, Ilse Stevens, Kurt Spittaels, Chris Van den Haute, Stefan Clerens, Gert Van den Bergh, Hugo Geerts, Fred Van Leuven, Frans Vandesande, Luc Moens

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2002

7

Proteomics analysis of the neurodegeneration in the brain of tau transgenic mice

Kelly Tilleman, Chris Van den Haute, Hugo Geerts, Fred van Leuven, Eddy L. Esmans, Luc Moens

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 125 KB

english, 2002

8

Preparation of Cyclo-Phen-Type Ligands: Chelators of Metal Ions as Potential Therapeutic Agents in the Treatment of Neurodegenerative Diseases

Christophe Boldron, Ingrid Van der Auwera, Céline Deraeve, Heinz Gornitzka, Stefaan Wera, Marguerite Pitié, Fred Van Leuven, Bernard Meunier

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 134 KB

english, 2005

9

Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β′-site increases Aβ generation

Lujia Zhou, Nathalie Brouwers, Iryna Benilova, Annelies Vandersteen, Marc Mercken, Koen Van Laere, Philip Van Damme, David Demedts, Fred Van Leuven, Kristel Sleegers, Kerensa Broersen, Christine Van B

Journal:

EMBO Molecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 820 KB

english, 2011

10

α2-macroglobulin and subacute-phase responses in Alzheimer's disease

Bart De Strooper, Fred Van Leuven

Journal:

Immunology Today

Année:

1993

Langue:

english

Fichier:

PDF, 134 KB

english, 1993

11

Isolation and partial characterisation of galactose-specific lectins from African yam beans, Sphenostyles stenocarpa Harms

Jesse S Machuka, Oladapo G Okeola, J.M Van Damme Els, Maarten J Chrispeels, Fred Van Leuven, Willy J Peumans

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 390 KB

english, 1999

12

Purification and characterization of strongly chitin-binding chitinases from salicylic acid-treated leek (Allium porrum)

Rudy Vergauwen, Fred Van Leuven, André Van Laere

Journal:

Physiologia Plantarum

Année:

1998

Fichier:

PDF, 1.25 MB

1998

13

The major elderberry (Sambucus nigra) fruit protein is a lectin derived from a truncated type 2 ribosome-inactivating protein

Els J.M. Van Damme, Soma Roy, Annick Barre, Pierre Rougé, Fred Van Leuven, Willy J. Peumans

Journal:

The Plant Journal

Année:

1997

Fichier:

PDF, 1.23 MB

1997

14

Purification, characterization and structural analysis of an abundant β-1,3-glucanase from banana fruit

Willy J. Peumans, Annick Barre, Veerle Derycke, Pierre Rougé, Wenling Zhang, Gregory D. May, Jan A. Delcour, Fred Van Leuven, Els J. M. Van Damme

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2000

15

Characterization and molecular cloning of two different type 2 ribosome-inactivating proteins from the monocotyledonous plant Polygonatum multiflorum

Els J. M. Van Damme, Qiang Hao, Diana Charels, Annick Barre, Pierre Rougé, Fred Van Leuven, Willy J. Peumans

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2000

16

Fruit-specific lectins from banana and plantain

Willy J. Peumans, Wenling Zhang, Annick Barre, Corinne Houlès Astoul, Peter J. Balint-Kurti, Paula Rovira, Pierre Rougé, Gregory D. May, Fred Van Leuven, Paolo Truffa-Bachi, Els J. M. Van Damme

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 274 KB

english, 2000

17

Purification and structural analysis of an abundant thaumatin-like protein from ripe banana fruit

Annick Barre, Willy J. Peumans, Laurence Menu-Bouaouiche, Els J. M. Van Damme, Gregory D. May, Arais Fernandez Herrera, Fred Van Leuven, Pierre Rougé

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 340 KB

english, 2000

18

Translocation of theHMGI-C(HMGA2) gene in a benign mesenchymoma (chondrolipoangioma)

Jo Van Dorpe, Paola Dal Cin, Stanislawa Weremowicz, Fred Van Leuven, Ivo de Wever, Herman Van den Berghe, Christopher Fletcher, Raf Sciot

Journal:

Virchows Archiv

Année:

2002

Langue:

english

Fichier:

PDF, 331 KB

english, 2002

19

Alpha-2-macroglobulin binds to the surface ofTrypanosoma cruzi

Cláudia M. L. Melo Coutinho, Guarani H. Cavalcanti, Fred van Leuven, Tania C. Araújo-Jorge, C. M. L. Melo Coutinho

Journal:

Parasitology Research

Année:

1997

Langue:

english

Fichier:

PDF, 684 KB

english, 1997

20

Detection of alpha-macroglobulin in the heart of mice infected withTrypanosoma cruzi

Cláudia M. L. M. Coutinho, Fred van Leuven, Tania C. Araújo-Jorge

Journal:

Parasitology Research

Année:

1999

Langue:

english

Fichier:

PDF, 726 KB

english, 1999

21

Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer’s disease

Harshvardhan Rolyan, Ann Caroline Feike, Ajeet Rijal Upadhaya, Andreas Waha, Tom Van Dooren, Christian Haass, Gerd Birkenmeier, Claus U. Pietrzik, Fred Van Leuven, Dietmar Rudolf Thal

Journal:

Journal of Neural Transmission

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

22

Loss of γ-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis

Dieter Lütjohann, Irfan Y. Tamboli, Kai Prager, Dietmar R. Thal, Karin M. Thelen, Ilse Dewachter, Claus U. Pietrzik, Peter St. George-Hyslop, Sangram S. Sisodia, Ulrike Müller, Fred van Leuven, Jochen

Journal:

Chemistry and Physics of Lipids

Année:

2008

Langue:

english

Fichier:

PDF, 50 KB

english, 2008

23

Role of presenilin1 in structural plasticity of cortical dendritic spines in vivo

Christian K. E. Jung, Martin Fuhrmann, Kamran Honarnejad, Fred Van Leuven, Jochen Herms

Journal:

Journal of Neurochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 374 KB

english, 2011

24

Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast

Thomas Vanhelmont, Tom Vandebroek, Ann De Vos, Dick Terwel, Katleen Lemaire, Jayamani Anandhakumar, Vanessa Franssens, Erwin Swinnen, Fred Van Leuven, Joris Winderickx

Journal:

FEMS Yeast Research

Année:

2010

Langue:

english

Fichier:

PDF, 557 KB

english, 2010

25

Characterization of α-synuclein aggregation and synergistic toxicity with protein tau in yeast

Piotr Zabrocki, Klaartje Pellens, Thomas Vanhelmont, Tom Vandebroek, Gerard Griffioen, Stefaan Wera, Fred Van Leuven, Joris Winderickx

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 755 KB

english, 2005

26

β-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins

Carlo Sala Frigerio, Julia V. Fadeeva, Aedín M. Minogue, Martin Citron, Fred Van Leuven, Matthias Staufenbiel, Paolo Paganetti, Dennis J. Selkoe, Dominic M. Walsh

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 616 KB

english, 2010

27

10.1038/34910

De Strooper, Bart, Saftig, Paul, Craessaerts, Katleen, Vanderstichele, Hugo, Guhde, Gundula, Annaert, Wim, Von Figura, Kurt, Van Leuven, Fred

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 382 KB

english, 1998

28

Isolation, characterization and molecular cloning of the mannose-binding lectins from leaves and roots of garlic (Allium sativum L.)

Koen Smeets, Els J.M. Van Damme, Peter Verhaert, Annick Barre, Pierre Rougé, Fred Van Leuven, Willy J. Peumans

Journal:

Plant Molecular Biology

Année:

1997

Langue:

english

Fichier:

PDF, 338 KB

english, 1997

29

Isolation, characterization and molecular cloning of a leaf-specific lectin from ramsons (Allium ursinum L.).

Koen Smeets, Els J.M. Van Damme, Fred Van Leuven, Willy J. Peumans

Journal:

Plant Molecular Biology

Année:

1997

Langue:

english

Fichier:

PDF, 77 KB

english, 1997

30

Isolation of a novel plant lectin with an unusual specificity fromCalystegia sepium

Willy J Peumans, Harry C Winter, Veronique Bemer, Fred Van Leuven, Irwin J Goldstein, Paolo Truffa-Bachi, Els J.M Van Damme

Journal:

Glycoconjugate Journal

Année:

1997

Langue:

english

Fichier:

PDF, 353 KB

english, 1997

31

Isolation and characterization of lectins and lectin-alliinase complexes from bulbs of garlic (Allium sativum) and ramsons (Allium ursinum)

Koen Smeets, Els J.M Van Damme, Fred Van Leuven, Willy J Peumans

Journal:

Glycoconjugate Journal

Année:

1997

Langue:

english

Fichier:

PDF, 842 KB

english, 1997

32

Isolation, characterization and molecular cloning of the bark lectins from Maackia amurensis

Els J.M Van Damme, Fred Van Leuven, Willy J Peumans

Journal:

Glycoconjugate Journal

Année:

1997

Langue:

english

Fichier:

PDF, 894 KB

english, 1997

33

Virosome-based active immunization targets soluble amyloid species rather than plaques in a transgenic mouse model of Alzheimer’s disease

Rinaldo Zurbriggen, Mario Amacker, Andreas R. Kammer, Nicole Westerfeld, Peter Borghgraef, Fred Van Leuven, Ingrid Van der Auwera, Stefaan Wera

Journal:

Journal of Molecular Neuroscience

Année:

2005

Langue:

english

Fichier:

PDF, 342 KB

english, 2005

34

Axonal transport, tau protein, and neurodegeneration in Alzheimer’s disease

Dick Terwel, Ilse Dewachter, Fred Van Leuven

Journal:

NeuroMolecular Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 364 KB

english, 2002

35

Identification of Glycogen Synthase Kinase-3 Inhibitors with a Selective Sting for Glycogen Synthase Kinase-3α

Lo Monte, Fabio, Kramer, Thomas, Gu, Jiamin, Anumala, Upendra Rao, Marinelli, Luciana, La Pietra, Valeria, Novellino, Ettore, Franco, Bénédicte, Demedts, David, Van Leuven, Fred

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2012

36

Trypanosoma cruzi: Acute Infection Affects Expression of α-2-Macroglobulin and A2MR/LRP Receptor Differently in C3H and C57BL/6 Mice

Maria de Nazaré C. Soeiro, Mauricio M. Paiva, Mariana C. Waghabi, Maria de Nazareth L. Meirelles, Kristin Lorent, Andrea Henriques-Pons, Claudia M.L.M. Coutinho, Fred Van Leuven, Tania C. Araújo-Jorge

Journal:

Experimental Parasitology

Année:

2000

Langue:

english

Fichier:

PDF, 3.03 MB

english, 2000

37

Mapping of human fibronectin receptorβsubunit gene to chromosome 10

Yong Zhang, Marc Saison, Marijke Spaepen, Bart De Strooper, Fred Van Leuven, Guido David, Herman Van den Berghe, Jean-Jacques Cassiman

Journal:

Somatic Cell and Molecular Genetics

Année:

1988

Langue:

english

Fichier:

PDF, 546 KB

english, 1988

38

Immunochemical characterization of a 150 000 dalton human fibroblast surface glycoprotein

Jos Verlinden, Fred Van Leuven, Jean-Jacques Cassiman, Herman Van Den Berghe

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Année:

1981

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1981

39

Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA

Fred Van Leuven, Lou Stas, Lucie Raymakers, Lut Overbergh, Bart De Strooper, Carl Hilliker, Kristin Lorent, Els Fias, Lieve Umans, Sophie Torrekens, Lutgarde Serneels, Diederik Moechars, Herman Van de

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1993

Langue:

english

Fichier:

PDF, 310 KB

english, 1993

40

Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes

Bart De Strooper, John W.M. Creemers, Dieder Moechers, Danny Huylebroeck, Wim J.M. Van De Ven, Fred Van Leuven, Herman Van den Berghe

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1995

Langue:

english

Fichier:

PDF, 446 KB

english, 1995

41

The trouble with PCR machines: fill up the empty spaces!

Fred Van Leuven

Journal:

Trends in Genetics

Année:

1991

Fichier:

PDF, 1.15 MB

1991

42

Astrocytic calcium/zinc binding protein S100A6 over expression in Alzheimer's disease and in PS1/APP transgenic mice models

Alain Boom, Roland Pochet, Michele Authelet, Laurent Pradier, Peter Borghgraef, Fred Van Leuven, Claus W. Heizmann, Jean-Pierre Brion

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2004

Langue:

english

Fichier:

PDF, 473 KB

english, 2004

43

Protein folding diseases and neurodegeneration: Lessons learned from yeast

Joris Winderickx, Charlotte Delay, Ann De Vos, Harald Klinger, Klaartje Pellens, Thomas Vanhelmont, Fred Van Leuven, Piotr Zabrocki

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2008

Langue:

english

Fichier:

PDF, 722 KB

english, 2008

44

Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson

Piotr Zabrocki, Ilse Bastiaens, Charlotte Delay, Tine Bammens, Ruben Ghillebert, Klaartje Pellens, Claudio De Virgilio, Fred Van Leuven, Joris Winderickx

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2008

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2008

45

Decreased expression of multidrug efflux transporters in the brains of GSK-3β transgenic mice

Joseph C. Lim, Zita Mickute, Monju Zaman, Sarah Hopkins, Hasini Wijesuriya, Thomas Steckler, Dieder Moechars, Fred Van Leuven, Zoltan Sarnyai, Stephen B. Hladky, Margery A. Barrand

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 720 KB

english, 2009

46

The Capsaicin Receptor TRPV1 Is a Crucial Mediator of the Noxious Effects of Mustard Oil

Wouter Everaerts, Maarten Gees, Yeranddy A. Alpizar, Ricard Farre, Cindy Leten, Aurelia Apetrei, Ilse Dewachter, Fred van Leuven, Rudi Vennekens, Dirk De Ridder, Bernd Nilius, Thomas Voets, Karel Tala

Journal:

Current Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2011

47

Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: A multi-electrode array study

Seon-Ah Chong, Iryna Benilova, Hamdy Shaban, Bart De Strooper, Herman Devijver, Dieder Moechars, Wolfgang Eberle, Carmen Bartic, Fred Van Leuven, Geert Callewaert

Journal:

Neurobiology of Disease

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

48

Isoflurane anesthesia precipitates tauopathy and upper airways dysfunction in pre-symptomatic Tau.P301L mice: Possible implication for neurodegenerative diseases

Clément Menuet, Peter Borghgraef, Nicolas Voituron, Christian Gestreau, Lies Gielis, Herman Devijver, Mathias Dutschmann, Fred Van Leuven, Gérard Hilaire

Journal:

Neurobiology of Disease

Année:

2012

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2012

49

Raphé tauopathy alters serotonin metabolism and breathing activity in terminal Tau.P301L mice: Possible implications for tauopathies and Alzheimer's disease

Clément Menuet, Peter Borghgraef, Valéry Matarazzo, Lies Gielis, Anne-Marie Lajard, Nicolas Voituron, Christian Gestreau, Mathias Dutschmann, Fred Van Leuven, Gérard Hilaire

Journal:

Respiratory Physiology & Neurobiology

Année:

2011

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2011

50

Functional expression of murine LRP1 requires correction of Lrp1 cDNA sequences

Liesbet Smeijers, Stefan Willems, Annick Lauwers, Els Thiry, Fred van Leuven, Anton J.M Roebroek

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2002

Langue:

english

Fichier:

PDF, 101 KB

english, 2002